Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables creatine:sodium symporter activity. Predicted to be involved in amino acid transport; protein catabolic process; and sodium ion transmembrane transport. Predicted to act upstream of or within creatine transmembrane transport. Predicted to be located in apical plasma membrane. Predicted to be active in glutamatergic synapse and postsynaptic membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study cerebral creatine deficiency syndrome 1. Human ortholog(s) of this gene implicated in cerebral creatine deficiency syndrome 1 and intellectual disability. Orthologous to human SLC6A8 (solute carrier family 6 member 8).