Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables double-stranded RNA binding activity. Involved in positive regulation of canonical NF-kappaB signal transduction and positive regulation of myeloid dendritic cell cytokine production. Acts upstream of or within response to exogenous dsRNA and response to virus. Located in cytoplasmic stress granule; cytosol; and mitochondrion. Is expressed in several structures, including 1st branchial arch; blastocyst; central nervous system; early embryo; and genitourinary system. Orthologous to human DDX1 (DEAD-box helicase 1).