Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables histone H3K27 methyltransferase activity and histone H3K4 methyltransferase activity. Acts upstream of or within negative regulation of DNA-templated transcription. Predicted to be located in chromosome. Predicted to be part of chromatin. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human NSD3 (nuclear receptor binding SET domain protein 3).