Automated description from the Alliance of Genome Resources (Release 7.0.0)
Involved in negative regulation of canonical Wnt signaling pathway; negative regulation of osteoblast differentiation; and positive regulation of fat cell differentiation. Acts upstream of or within positive regulation of bone resorption; positive regulation of osteoclast differentiation; and regulation of cytosolic calcium ion concentration. Located in endoplasmic reticulum. Is expressed in several structures, including brain; head mesenchyme; retina nuclear layer; thymus primordium; and vibrissa. Orthologous to human TMEM64 (transmembrane protein 64).