Automated description from the Alliance of Genome Resources (Release 6.0.0)
Predicted to enable several functions, including GABA receptor binding activity; guanyl-nucleotide exchange factor activity; and protein kinase A regulatory subunit binding activity. Predicted to be involved in several processes, including Golgi to plasma membrane transport; positive regulation of tumor necrosis factor production; and receptor recycling. Predicted to act upstream of or within intracellular signal transduction. Predicted to be located in several cellular components, including Golgi apparatus; microtubule cytoskeleton; and recycling endosome. Predicted to be active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and postsynapse. Is expressed in brown fat; central nervous system; duodenum; thymus; and trunk. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2).