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Automated description from the Alliance of Genome Resources (Release 8.3.0)

Predicted to enable chemokine activity. Predicted to contribute to wide pore channel activity. Predicted to be involved in several processes, including complement activation; negative regulation of macrophage chemotaxis; and positive regulation of cytokine production. Predicted to be located in extracellular region. Predicted to be part of membrane attack complex. Predicted to be active in extracellular space and other organism cell membrane. Human ortholog(s) of this gene implicated in several diseases, including complement component 5 deficiency; liver cirrhosis; neutropenia; paroxysmal nocturnal hemoglobinuria; and pneumonia. Orthologous to human C5 (complement C5).

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Gene Ontology Evidence Code Abbreviations:

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