Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables extracellularly ATP-gated cation channel activity. Acts upstream of or within cation transmembrane transport and excitatory postsynaptic potential. Predicted to be located in cytosol and plasma membrane. Predicted to be active in nuclear inner membrane. Is expressed in several structures, including forelimb bud; nervous system; neural ectoderm; olfactory epithelium; and retina. Orthologous to human P2RX5 (purinergic receptor P2X 5).