Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription factor binding activity; histone H3K deacetylase activity; and transcription corepressor activity. Involved in negative regulation of gene expression, epigenetic. Acts upstream of or within several processes, including determination of adult lifespan; negative regulation of transcription by RNA polymerase II; and regulation of myotube differentiation. Part of histone methyltransferase complex. Is expressed in several structures, including 2-cell stage embryo; heart; musculoskeletal system; nervous system; and trunk myotome. Orthologous to human HDAC9 (histone deacetylase 9).