Automated description from the Alliance of Genome Resources (Release 8.3.0)
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including embryonic limb morphogenesis; kidney development; and skeletal system development. Acts upstream of or within embryonic skeletal system morphogenesis; negative regulation of transcription by RNA polymerase II; and positive regulation of cell population proliferation. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human OSR2 (odd-skipped related transciption factor 2).
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