Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables iron-responsive element binding activity. Involved in osteoclast differentiation. Acts upstream of or within several processes, including erythrocyte homeostasis; multicellular organismal-level iron ion homeostasis; and protoporphyrinogen IX biosynthetic process. Located in cytosol. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; liver; nervous system; and yolk sac. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human IREB2 (iron responsive element binding protein 2).