Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Acts upstream of or within negative regulation of protein localization to cilium and phosphatidylinositol dephosphorylation. Located in Golgi membrane; axoneme; and nucleus. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in Joubert syndrome and Joubert syndrome 1. Orthologous to human INPP5E (inositol polyphosphate-5-phosphatase E).