Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables sodium:bicarbonate symporter activity. Acts upstream of or within bicarbonate transport; establishment of localization in cell; and sodium ion transport. Located in basolateral plasma membrane. Is expressed in several structures, including brain; metanephros; spinal cord floor plate; and thyroid primordium. Used to study renal tubular acidosis. Human ortholog(s) of this gene implicated in renal tubular acidosis. Orthologous to human SLC4A4 (solute carrier family 4 member 4).