Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable anaphase-promoting complex binding activity; ubiquitin ligase activator activity; and ubiquitin ligase-substrate adaptor activity. Involved in negative regulation of cellular senescence and positive regulation of cell population proliferation. Acts upstream of or within lens fiber cell differentiation; proteolysis involved in protein catabolic process; and regulation of meiotic nuclear division. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be part of anaphase-promoting complex. Is expressed in several structures, including central nervous system; early conceptus; oocyte; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 109. Orthologous to human FZR1 (fizzy and cell division cycle 20 related 1).