Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables leukotriene receptor activity. Acts upstream of or within several processes, including calcium ion transport; chemotaxis; and inflammatory response to antigenic stimulus. Located in plasma membrane. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in allergic disease; asthma; and rhinitis. Orthologous to human CYSLTR1 (cysteinyl leukotriene receptor 1).