Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within several processes, including adult walking behavior; proteasome-mediated ubiquitin-dependent protein catabolic process; and response to activity. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Used to study hereditary ataxia. Human ortholog(s) of this gene implicated in autosomal dominant sensory ataxia 1 and hereditary spastic paraplegia 85. Orthologous to human RNF170 (ring finger protein 170).