Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable DNA end binding activity and DNA polymerase binding activity. Involved in double-strand break repair via nonhomologous end joining. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be part of DNA ligase IV complex and DNA-dependent protein kinase-DNA ligase 4 complex. Predicted to be active in site of double-strand break. Human ortholog(s) of this gene implicated in severe combined immunodeficiency. Orthologous to human NHEJ1 (non-homologous end joining factor 1).