Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable several functions, including identical protein binding activity; phosphorylation-dependent protein binding activity; and protein serine/threonine kinase activator activity. Predicted to be involved in several processes, including broken chromosome clustering; double-strand break repair; and mitotic G2/M transition checkpoint. Predicted to act upstream of or within reciprocal meiotic recombination. Located in condensed nuclear chromosome and male germ cell nucleus. Is expressed in cerebral cortex ventricular layer; embryo; and metanephros. Orthologous to human TOPBP1 (DNA topoisomerase II binding protein 1).