Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables PDZ domain binding activity. Involved in regulation of short-term neuronal synaptic plasticity. Located in dendritic spine membrane; postsynaptic density; and postsynaptic membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in brain. Orthologous to human SHISA9 (shisa family member 9).