Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ubiquitin ligase-substrate adaptor activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and regulation of inflammatory response. Acts upstream of or within protein monoubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be part of SCF ubiquitin ligase complex. Is expressed in dorsal root ganglion; glossopharyngeal ganglion; and trigeminal ganglion. Orthologous to human FBXL2 (F-box and leucine rich repeat protein 2).