Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to contribute to ubiquitin-protein transferase activity. Acts upstream of or within response to UV and response to X-ray. Predicted to be located in nuclear matrix and perikaryon. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex and nucleotide-excision repair complex. Used to study Cockayne syndrome. Human ortholog(s) of this gene implicated in Cockayne syndrome; Cockayne syndrome A; and UV-sensitive syndrome. Orthologous to human ERCC8 (ERCC excision repair 8, CSA ubiquitin ligase complex subunit).