Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable 3'-flap endonuclease activity. Predicted to contribute to crossover junction DNA endonuclease activity. Predicted to be involved in DNA metabolic process; mitotic intra-S DNA damage checkpoint signaling; and osteoblast proliferation. Predicted to act upstream of or within DNA catabolic process and response to intra-S DNA damage checkpoint signaling. Predicted to be part of Holliday junction resolvase complex. Predicted to be active in nucleus and replication fork. Used to study Marfan syndrome; arterial tortuosity syndrome; and pulmonary emphysema. Orthologous to human MUS81 (MUS81 structure-specific endonuclease subunit).