Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable 3-dehydrosphinganine reductase activity. Acts upstream of or within sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Is expressed in skin. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis et progressiva 4 and follicular lymphoma. Orthologous to human KDSR (3-ketodihydrosphingosine reductase).