Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including cAMP binding activity; guanyl-nucleotide exchange factor activity; and small GTPase binding activity. Involved in positive regulation of insulin secretion and regulation of synaptic vesicle cycle. Acts upstream of or within with a positive effect on hormone secretion. Acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway; regulation of exocytosis; and secretion by cell. Is active in cytosol and hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including adrenal gland; ganglia; heart; lung; and metanephros. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human RAPGEF4 (Rap guanine nucleotide exchange factor 4).