Automated description from the Alliance of Genome Resources (Release 7.5.0)
Predicted to enable several functions, including heat shock protein binding activity; histone deacetylase activity; and histone decrotonylase activity. Predicted to be involved in several processes, including cellular response to forskolin; cellular response to trichostatin A; and regulation of macromolecule metabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of histone deacetylase complex. Is expressed in several structures, including 2-cell stage embryo; brain; embryo ectoderm; foregut; and retina. Used to study Cornelia de Lange syndrome 5. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 5 and Wilson-Turner syndrome. Orthologous to human HDAC8 (histone deacetylase 8).
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