Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable methyltransferase activity. Predicted to be involved in protein histidyl modification to diphthamide. Predicted to act upstream of or within methylation. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with short stature, prominent forehead, and feeding difficulties. Orthologous to human DPH5 (diphthamide biosynthesis 5).