Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables ATP binding activity; magnesium ion binding activity; and protein kinase activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of protein metabolic process; and protein stabilization. Acts upstream of or within positive regulation of dopamine secretion; positive regulation of dopaminergic synaptic transmission; and positive regulation of mitochondrial electron transport, NADH to ubiquinone. Located in endoplasmic reticulum and mitochondrial inner membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Used to study Parkinson's disease 6. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 6. Orthologous to human PINK1 (PTEN induced kinase 1).