Automated description from the Alliance of Genome Resources (Release 8.3.0)
Predicted to enable ubiquitin conjugating enzyme activity and ubiquitin-like protein ligase binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including anaphase-promoting complex-dependent catabolic process; protein polyubiquitination; and regulation of mitotic cell cycle phase transition. Predicted to act upstream of or within SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and positive regulation of mitotic metaphase/anaphase transition. Predicted to be located in cytosol and plasma membrane. Predicted to be part of anaphase-promoting complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; neural retina; and spleen. Orthologous to human UBE2C (ubiquitin conjugating enzyme E2 C).
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