Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables Wnt-protein binding activity and frizzled binding activity. Acts upstream of or within several processes, including establishment of planar polarity involved in neural tube closure; inner ear development; and negative regulation of canonical Wnt signaling pathway. Located in sarcoplasm. Is expressed in several structures, including genitourinary system; heart; meninges; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in Barrett's esophagus. Orthologous to human CTHRC1 (collagen triple helix repeat containing 1).