Automated description from the Alliance of Genome Resources (Release 7.1.0)
Acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Predicted to be located in endoplasmic reticulum and nuclear membrane. Predicted to be part of monoatomic ion channel complex. Is expressed in central nervous system; early conceptus; retina; and secondary oocyte. Orthologous to human TMEM109 (transmembrane protein 109).