Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable DNA exonuclease activity. Predicted to be involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and response to ionizing radiation. Predicted to act upstream of or within DNA damage response and apoptotic process. Predicted to be located in nuclear membrane; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Is expressed in cerebral cortex and telencephalon. Orthologous to human AEN (apoptosis enhancing nuclease).