Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable protein dimerization activity and ubiquitin protein ligase activity. Predicted to be involved in double-strand break repair via homologous recombination. Predicted to act upstream of or within DNA recombination. Located in chromosome, centromeric region; mitotic spindle pole; and nucleus. Part of Smc5-Smc6 complex. Is expressed in cerebral cortex ventricular layer; cortical plate; and pancreas epithelium. Orthologous to human NSMCE1 (NSE1 homolog, SMC5-SMC6 complex component).