Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable ubiquitin ligase complex scaffold activity; ubiquitin protein ligase activity; and ubiquitin protein ligase binding activity. Involved in several processes, including cellular response to UV; in utero embryonic development; and ribosome biogenesis. Acts upstream of or within several processes, including negative regulation of granulocyte differentiation; regulation of cell cycle phase transition; and regulation of nucleotide-excision repair. Part of Cul4A-RING E3 ubiquitin ligase complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and musculoskeletal system. Orthologous to human CUL4A (cullin 4A).