Automated description from the Alliance of Genome Resources (Release 7.0.0)
Involved in positive regulation of apoptotic process. Acts upstream of or within intrinsic apoptotic signaling pathway in response to oxidative stress and neuron apoptotic process. Located in cytoplasmic side of plasma membrane and mitochondrion. Part of CD40 receptor complex. Is expressed in several structures, including cochlea; early conceptus; ganglia; pancreas epithelium; and trigeminal nerve. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 64. Orthologous to human DIABLO (diablo IAP-binding mitochondrial protein).