Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables several functions, including histone deacetylase binding activity; peroxisome proliferator activated receptor binding activity; and phosphatidate phosphatase activity. Involved in several processes, including mitochondrial fission; positive regulation of cold-induced thermogenesis; and triglyceride metabolic process. Acts upstream of or within several processes, including cellular response to insulin stimulus; negative regulation of transcription by RNA polymerase II; and ruffle organization. Located in endoplasmic reticulum; mitochondrial outer membrane; and nuclear membrane. Part of transcription regulator complex. Is active in endoplasmic reticulum membrane. Is expressed in liver; nervous system; olfactory epithelium; and tooth. Used to study lipodystrophy. Orthologous to human LPIN1 (lipin 1).