Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cell fate commitment; pituitary gland development; and regulation of DNA-templated transcription. Predicted to be part of chromatin. Predicted to be active in nucleus. Is expressed in central nervous system; early conceptus; future adenohypophysis; and genitourinary system. Used to study adrenocorticotropic hormone deficiency. Human ortholog(s) of this gene implicated in adrenocorticotropic hormone deficiency; alcohol dependence; and inherited metabolic disorder. Orthologous to human TBX19 (T-box transcription factor 19).