Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables PDZ domain binding activity; protein homodimerization activity; and signaling receptor binding activity. Involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and synapse organization. Acts upstream of or within several processes, including calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; synapse assembly; and unidimensional cell growth. Located in several cellular components, including basolateral plasma membrane; dendrite; and synaptic vesicle. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and synaptic membrane. Is expressed in several structures, including metanephros; nervous system; respiratory system; sensory organ; and tooth. Human ortholog(s) of this gene implicated in breast carcinoma and prostate cancer. Orthologous to human CADM1 (cell adhesion molecule 1).