Automated description from the Alliance of Genome Resources (Release 8.3.0)
Enables PDZ domain binding activity; protein homodimerization activity; and signaling receptor binding activity. Involved in several processes, including heterophilic cell-cell adhesion; homophilic cell-cell adhesion; and synapse organization. Acts upstream of or within several processes, including calcium-independent cell-cell adhesion; synapse assembly; and unidimensional cell growth. Located in several cellular components, including basolateral plasma membrane; cell body fiber; and varicosity. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and synaptic membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system; and sensory organ. Human ortholog(s) of this gene implicated in breast carcinoma and prostate cancer. Orthologous to human CADM1 (cell adhesion molecule 1).
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