Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables GTP binding activity; GTPase activity; and myosin V binding activity. Acts upstream of or within several processes, including melanocyte differentiation; melanosome transport; and secretion by cell. Located in Golgi apparatus; cytoplasmic vesicle; and photoreceptor outer segment. Is expressed in 4-cell stage embryo; endocrine gland; lip; paravertebral ganglion; and thymus primordium. Used to study Hermansky-Pudlak syndrome 1; hemophagocytic lymphohistiocytosis; and platelet storage pool deficiency. Human ortholog(s) of this gene implicated in Griscelli syndrome type 2 and non-Langerhans-cell histiocytosis. Orthologous to human RAB27A (RAB27A, member RAS oncogene family).