Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable several functions, including RNA polymerase II-specific DNA-binding transcription factor binding activity; cytoskeletal protein binding activity; and transmembrane transporter binding activity. Predicted to be involved in several processes, including negative regulation of signal transduction; positive regulation of protein metabolic process; and proteasome regulatory particle assembly. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytosol and intermediate filament cytoskeleton. Predicted to be part of proteasome regulatory particle, base subcomplex. Predicted to be active in several cellular components, including cytoskeleton; neuron projection; and nucleus. Is expressed in limb and limb mesenchyme. Orthologous to human PSMD10 (proteasome 26S subunit, non-ATPase 10).