Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables protein homodimerization activity; signaling receptor binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of mitochondrial depolarization; negative regulation of programmed cell death; and positive regulation of response to endoplasmic reticulum stress. Acts upstream of or within neuron apoptotic process. Located in several cellular components, including bounding membrane of organelle; mitochondrial membrane; and trans-Golgi network membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; gut; retina; and vibrissa dermal component. Orthologous to human BOK (BCL2 family apoptosis regulator BOK).