Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables kinase inhibitor activity. Involved in negative regulation of CD8-positive, alpha-beta T cell differentiation and positive regulation of CD4-positive, alpha-beta T cell differentiation. Acts upstream of or within several processes, including cell surface receptor signaling pathway; fat cell differentiation; and negative regulation of signal transduction. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Is expressed in several structures, including adipose tissue; genitourinary system; gut; hemolymphoid system gland; and nervous system. Human ortholog(s) of this gene implicated in acute myeloid leukemia; gastrointestinal system cancer (multiple); reproductive organ cancer (multiple); and urinary bladder cancer. Orthologous to human SOCS1 (suppressor of cytokine signaling 1).