Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable protein kinase binding activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; and regulation of mitotic nuclear division. Part of SCF ubiquitin ligase complex. Is expressed in central nervous system; embryo; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human FBXW5 (F-box and WD repeat domain containing 5).