Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables thiamine diphosphokinase activity. Involved in thiamine diphosphate biosynthetic process. Acts upstream of or within thiamine metabolic process. Is active in cytosol. Is expressed in several structures, including gonad; heart; liver; lung; and spleen. Human ortholog(s) of this gene implicated in inherited metabolic disorder. Orthologous to human TPK1 (thiamin pyrophosphokinase 1).