Automated description from the Alliance of Genome Resources (Release 6.0.0)
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; nuclear glucocorticoid receptor binding activity; and protein heterodimerization activity. Involved in several processes, including cellular response to corticotropin-releasing hormone stimulus; dopaminergic neuron differentiation; and fat cell differentiation. Acts upstream of or within several processes, including dopamine biosynthetic process; nervous system development; and response to amphetamine. Located in nucleus. Is expressed in several structures, including ear; endocrine gland; genitourinary system; integumental system; and nervous system. Used to study Parkinson's disease and schizophrenia. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human NR4A2 (nuclear receptor subfamily 4 group A member 2).