Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables deoxyguanosine kinase activity. Acts upstream of or within dGTP metabolic process; deoxyribonucleoside monophosphate biosynthetic process; and nucleotide biosynthetic process. Located in cytosol and mitochondrion. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 4; mitochondrial DNA depletion syndrome 3; and mitochondrial metabolism disease. Orthologous to human DGUOK (deoxyguanosine kinase).