Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables JUN kinase activity and protein serine/threonine/tyrosine kinase activity. Involved in several processes, including inflammatory response to wounding; positive regulation of macromolecule metabolic process; and regulation of circadian rhythm. Acts upstream of or within several processes, including positive regulation of podosome assembly; protein localization to tricellular tight junction; and response to cadmium ion. Located in cytosol and mitochondrion. Is active in Schaffer collateral - CA1 synapse and cytoplasm. Is expressed in several structures, including alimentary system; brain; future brain; genitourinary system; and olfactory epithelium. Human ortholog(s) of this gene implicated in colorectal cancer; pancreatic adenocarcinoma; and type 2 diabetes mellitus. Orthologous to human MAPK9 (mitogen-activated protein kinase 9).