Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables heparanase activity. Involved in several processes, including heparan sulfate proteoglycan catabolic process; positive regulation of osteoblast proliferation; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in membrane raft and nucleus. Is active in extracellular space. Is expressed in oral region gland; sensory organ; skeleton; submandibular gland primordium; and urinary system. Orthologous to human HPSE (heparanase).