Gene Ontology Classifications

Symbol
Name
ID

Kat2b
K(lysine) acetyltransferase 2B
MGI:1343094

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Automated description from the Alliance of Genome Resources (Release 9.0.0)

Enables several functions, including L-lysine N6-acetyltransferase activity, acting on acetyl phosphate as donor; cyclin-dependent protein serine/threonine kinase inhibitor activity; and histone H3K9 acetyltransferase activity. Involved in internal peptidyl-lysine acetylation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; and positive regulation of transcription from RNA polymerase II promoter by glucose. Acts upstream of or within positive regulation of gluconeogenesis and positive regulation of transcription by RNA polymerase II. Located in actomyosin; kinetochore; and sarcomere. Part of ATAC complex. Is active in nucleus. Is expressed in several structures, including 4-8 cell stage conceptus; blastocyst-stage conceptus; genitourinary system; hemolymphoid system gland; and lung. Orthologous to human KAT2B (lysine acetyltransferase 2B).

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Aspect

Category

Evidence

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

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Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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