Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable identical protein binding activity and kinetochore binding activity. Acts upstream of or within negative regulation of T cell proliferation; regulation of mitotic cell cycle phase transition; and thymus development. Located in cytoplasm; kinetochore; and spindle pole. Part of MAD1 complex and mitotic spindle assembly checkpoint MAD1-MAD2 complex. Is expressed in brain; cerebral cortex; future brain; hippocampus; and telencephalon. Human ortholog(s) of this gene implicated in lymphoma; mosaic variegated aneuploidy syndrome; and prostate cancer. Orthologous to human MAD1L1 (mitotic arrest deficient 1 like 1).