Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables protein kinase binding activity. Involved in several processes, including autophagosome assembly; positive regulation of autophagy; and regulation of protein lipidation. Acts upstream of or within several processes, including defense response to symbiont; positive regulation of cell size; and regulation of signal transduction. Located in autophagosome membrane; nucleus; and phagophore assembly site membrane. Part of Atg1/ULK1 kinase complex. Is expressed in several structures, including cerebral cortex; ganglia; heart; musculoskeletal system; and trunk paraxial mesenchyme. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human RB1CC1 (RB1 inducible coiled-coil 1).