Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables several functions, including macrophage colony-stimulating factor receptor activity; protein homodimerization activity; and protein phosphatase binding activity. Involved in several processes, including cell surface receptor signaling pathway; nervous system development; and positive regulation of intracellular signal transduction. Located in cell surface and plasma membrane. Part of CSF1-CSF1R complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and limb. Human ortholog(s) of this gene implicated in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia; diabetes mellitus; gastrointestinal system cancer (multiple); lung cancer (multiple); and renal cell carcinoma. Orthologous to human CSF1R (colony stimulating factor 1 receptor).